How can polyreactive antibodies conquer rapidly evolving viruses?
نویسندگان
چکیده
Broadly neutralizing antibodies against rapidly evolving viruses (e.g., HIV-1 and influenza virus), often manifest antigen-binding promiscuity. Based on a recent study, we hypothesize the significance of antibody polyreactivity in neutralization viruses. We propose that contributes to toleration viral variants shortens time for generating antibodies.
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ژورنال
عنوان ژورنال: Trends in Immunology
سال: 2021
ISSN: ['1471-4981', '1471-4906']
DOI: https://doi.org/10.1016/j.it.2021.06.008